Functional in vivo characterization of sox10 enhancers in neural crest and melanoma development
By performing ATAC-Seq on zebrafish melanoma tumours, Cunningham et al identify putative sox10 enhancers with embryonic activity in zebrafish. They identify a region upstream of sox10, termed peak5, that is needed for full expression of embryonic sox10 and for adult stripe patterning demonstrating a...
Main Authors: | Rebecca L. Cunningham, Eva T. Kramer, Sophia K. DeGeorgia, Paula M. Godoy, Anna P. Zarov, Shayana Seneviratne, Vadim Grigura, Charles K. Kaufman |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-06-01
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Series: | Communications Biology |
Online Access: | https://doi.org/10.1038/s42003-021-02211-0 |
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