Development of monoclonal antibodies and immunoassays for sensitive and specific detection of Shiga toxin Stx2f.

BACKGROUND: Shiga toxin 2 (Stx2) is a major virulence factor in gastrointestinal diseases caused by Escherichia coli. Although Stx2a (prototypical Stx2) is well-studied, all seven subtypes of Stx2 have been associated with disease in mammals. Several subtypes of Stx2, including Stx2f, are difficult...

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Bibliographic Details
Main Authors: Craig Skinner, Stephanie Patfield, Larry Stanker, Xiaohua He
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3775747?pdf=render

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