| Summary: | Background/Aim. It had been suggested that elevated body mass index (BMI) is
a beneficial and preventive factor when it comes to the outcome for patients
undergoing coronary artery bypass grafting (CABG). At the same time, obesity
is strongly associated with coronary artery disease development. The aim of
this study was to determine the significance of the obesity paradox in
patients referred for CABG and to examine if a relationship exists between
obesity and early coronary surgery outcome. Methods. This study comparised
791 patients who had undergone isolated CABG over one year period (year
2010). The average age of patients was 62.33 ± 8.12 years and involved 568
(71.8%) male and 223 (28.2%) female patients, while the mean logistic
EuroSCORE was 3.42%. The patients were categorized into three distinct groups
based on their BMI: I - BMI < 24.9 kg/m2; II - BMI 25-30 kg/m2; III - BMI >
30 kg/m2. Regression analysis was conducted to determine whether BMI was an
independent predictor of early mortality after CABG. Results. The majority of
the cohort could be categorized as overweight (49%) or obese (30%). There was
no association between BMI and gender (p = 0.398). The overall early
mortality was 2.15% (1.85% in the group I, 2.06% in the group II and 2.51% in
the group III; p = 0.869). Univariate analysis showed that obesity cannot be
regarded as an independent risk factor for early mortality following CABG
(odds ratio 1.021, 95% confidence interval 0.910-1.145, p = 0.724). Duration
of in-hospital period following the surgery was comparable within the BMI
groups (p = 0.502). Conclusion. Compared to non-obese patients, overweight
and obese individuals have similar early mortality rate following CABG. This
study can substantiate the presence of obesity paradox only in terms that
elevated BMI patients have comparable outcome with non-obese. Further
research is needed to delineate potential underlying mechanisms that set off
obesity to protective factor for coronary surgery.
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