The migration of metastatic breast cancer cells is regulated by matrix stiffness via YAP signalling

Matrix stiffness is a driver of breast cancer progression and mechanosensitive transcriptional activator YAP plays an important role in this process. However, the interplay between breast cancer and matrix stiffness, and the significance of this interplay remained largely unknown. Here, we showed an...

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Bibliographic Details
Main Authors: Wei Chen, Shihyun Park, Chrishma Patel, Yuxin Bai, Karim Henary, Arjun Raha, Saeed Mohammadi, Lidan You, Fei Geng
Format: Article
Language:English
Published: Elsevier 2021-02-01
Series:Heliyon
Subjects:
YAP
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844021003571