Combined cell and nanoparticle models for TOPAS to study radiation dose enhancement in cell organelles

Abstract Dose enhancement by gold nanoparticles (AuNP) increases the biological effectiveness of radiation damage in biomolecules and tissue. To apply them effectively during cancer therapy their influence on the locally delivered dose has to be determined. Hereby, the AuNP locations strongly influe...

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Bibliographic Details
Main Authors: Marc Benjamin Hahn, Julián Mateo Zutta Villate
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-85964-2