Oyster Versatile IKKα/βs Are Involved in Toll-Like Receptor and RIG-I-Like Receptor Signaling for Innate Immune Response

Oyster Versatile IKKα/βs Are Involved in Toll-Like Receptor and RIG-I-Like Receptor Signaling for Innate Immune Response

IκB kinases (IKKs) play critical roles in innate immunity through signal-induced activation of the key transcription factors nuclear factor-κB (NF-κB) and interferon regulatory factors (IRFs). However, studies of invertebrate IKK functions remain scarce. In this study, we performed phylogenetic anal...

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Bibliographic Details
Main Authors: Baoyu Huang, Linlin Zhang, Fei Xu, Xueying Tang, Li Li, Wei Wang, Mingkun Liu, Guofan Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Immunology
Subjects:
Crassostrea gigas
innate immunity
IKKα
IKKβ
Toll-like receptor
RIG-I-like receptor
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01826/full

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