Cerebral Rhizomucor Infection Treated by Posaconazole Delayed-Release Tablets in an Allogeneic Stem Cell Transplant Recipient

Mucormycosis (zygomycosis) is an emerging fungal disease in allogeneic hematopoietic stem cell transplant (allo-HSCT) recipients. A 30-year-old woman diagnosed with acute myelomonocytic leukemia and needing allo-HSCT presented pulmonary and cerebral infection due to Rhizomucor pusillus. This fungal...

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Main Authors: Diego O. Andrey, Laurent Kaiser, Stéphane Emonet, Veronique Erard, Yves Chalandon, Christian van Delden
Format: Article
Language:English
Published: Elsevier 2017-02-01
Series:International Journal of Infectious Diseases
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1201971216316575
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spelling doaj-84495dd6e8934b2d96b65a20fff3fc0d2020-11-25T00:53:17ZengElsevierInternational Journal of Infectious Diseases1201-97121878-35112017-02-0155C242610.1016/j.ijid.2016.12.014Cerebral Rhizomucor Infection Treated by Posaconazole Delayed-Release Tablets in an Allogeneic Stem Cell Transplant RecipientDiego O. Andrey0Laurent Kaiser1Stéphane Emonet2Veronique Erard3Yves Chalandon4Christian van Delden5Service of Infectious Diseases, Department of Medical Specialties, Geneva University Hospitals, Rue Gabrielle-Perret-Gentil 4, 1211 Geneva 14, SwitzerlandService of Infectious Diseases, Department of Medical Specialties, Geneva University Hospitals, Rue Gabrielle-Perret-Gentil 4, 1211 Geneva 14, SwitzerlandService of Infectious Diseases, Department of Medical Specialties, Geneva University Hospitals, Rue Gabrielle-Perret-Gentil 4, 1211 Geneva 14, SwitzerlandService of Infectious Diseases, Hôpital Fribourgeois, Chemin des Pensionnats 2, 1708 Fribourg, SwitzerlandService of Hematology, Department of Medical Specialties, Geneva University Hospitals, Rue Gabrielle-Perret-Gentil 4, 1211 Geneva 14, SwitzerlandService of Infectious Diseases, Department of Medical Specialties, Geneva University Hospitals, Rue Gabrielle-Perret-Gentil 4, 1211 Geneva 14, SwitzerlandMucormycosis (zygomycosis) is an emerging fungal disease in allogeneic hematopoietic stem cell transplant (allo-HSCT) recipients. A 30-year-old woman diagnosed with acute myelomonocytic leukemia and needing allo-HSCT presented pulmonary and cerebral infection due to Rhizomucor pusillus. This fungal infection was treated with surgical treatment and posaconazole delayed-release tablets. This strategy allowed reaching high drug levels that could not be obtained with the posaconazole solution.http://www.sciencedirect.com/science/article/pii/S1201971216316575Posaconazole delayed-release tabletsRhizomucor pusillusZygomycosisMucormycosis
collection DOAJ
language English
format Article
sources DOAJ
author Diego O. Andrey
Laurent Kaiser
Stéphane Emonet
Veronique Erard
Yves Chalandon
Christian van Delden
spellingShingle Diego O. Andrey
Laurent Kaiser
Stéphane Emonet
Veronique Erard
Yves Chalandon
Christian van Delden
Cerebral Rhizomucor Infection Treated by Posaconazole Delayed-Release Tablets in an Allogeneic Stem Cell Transplant Recipient
International Journal of Infectious Diseases
Posaconazole delayed-release tablets
Rhizomucor pusillus
Zygomycosis
Mucormycosis
author_facet Diego O. Andrey
Laurent Kaiser
Stéphane Emonet
Veronique Erard
Yves Chalandon
Christian van Delden
author_sort Diego O. Andrey
title Cerebral Rhizomucor Infection Treated by Posaconazole Delayed-Release Tablets in an Allogeneic Stem Cell Transplant Recipient
title_short Cerebral Rhizomucor Infection Treated by Posaconazole Delayed-Release Tablets in an Allogeneic Stem Cell Transplant Recipient
title_full Cerebral Rhizomucor Infection Treated by Posaconazole Delayed-Release Tablets in an Allogeneic Stem Cell Transplant Recipient
title_fullStr Cerebral Rhizomucor Infection Treated by Posaconazole Delayed-Release Tablets in an Allogeneic Stem Cell Transplant Recipient
title_full_unstemmed Cerebral Rhizomucor Infection Treated by Posaconazole Delayed-Release Tablets in an Allogeneic Stem Cell Transplant Recipient
title_sort cerebral rhizomucor infection treated by posaconazole delayed-release tablets in an allogeneic stem cell transplant recipient
publisher Elsevier
series International Journal of Infectious Diseases
issn 1201-9712
1878-3511
publishDate 2017-02-01
description Mucormycosis (zygomycosis) is an emerging fungal disease in allogeneic hematopoietic stem cell transplant (allo-HSCT) recipients. A 30-year-old woman diagnosed with acute myelomonocytic leukemia and needing allo-HSCT presented pulmonary and cerebral infection due to Rhizomucor pusillus. This fungal infection was treated with surgical treatment and posaconazole delayed-release tablets. This strategy allowed reaching high drug levels that could not be obtained with the posaconazole solution.
topic Posaconazole delayed-release tablets
Rhizomucor pusillus
Zygomycosis
Mucormycosis
url http://www.sciencedirect.com/science/article/pii/S1201971216316575
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