Cerebral Rhizomucor Infection Treated by Posaconazole Delayed-Release Tablets in an Allogeneic Stem Cell Transplant Recipient

Cerebral Rhizomucor Infection Treated by Posaconazole Delayed-Release Tablets in an Allogeneic Stem Cell Transplant Recipient

Mucormycosis (zygomycosis) is an emerging fungal disease in allogeneic hematopoietic stem cell transplant (allo-HSCT) recipients. A 30-year-old woman diagnosed with acute myelomonocytic leukemia and needing allo-HSCT presented pulmonary and cerebral infection due to Rhizomucor pusillus. This fungal...

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Bibliographic Details
Main Authors: Diego O. Andrey, Laurent Kaiser, Stéphane Emonet, Veronique Erard, Yves Chalandon, Christian van Delden
Format: Article
Language:English
Published: Elsevier 2017-02-01
Series:International Journal of Infectious Diseases
Subjects:
Posaconazole delayed-release tablets
Rhizomucor pusillus
Zygomycosis
Mucormycosis
Online Access:http://www.sciencedirect.com/science/article/pii/S1201971216316575
Description
Summary:Mucormycosis (zygomycosis) is an emerging fungal disease in allogeneic hematopoietic stem cell transplant (allo-HSCT) recipients. A 30-year-old woman diagnosed with acute myelomonocytic leukemia and needing allo-HSCT presented pulmonary and cerebral infection due to Rhizomucor pusillus. This fungal infection was treated with surgical treatment and posaconazole delayed-release tablets. This strategy allowed reaching high drug levels that could not be obtained with the posaconazole solution.
ISSN:1201-9712
1878-3511

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