An Army Marches on Its Stomach: Metabolic Intermediates as Antimicrobial Mediators in Mycobacterium tuberculosis Infection
The cells of the immune system are reliant on their metabolic state to launch effective responses to combat mycobacterial infections. The bioenergetic profile of the cell determines the molecular fuels and metabolites available to the host, as well as to the bacterial invader. How cells utilize the...
Main Authors: | Emer E. Hackett, Frederick J. Sheedy |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2020-08-01
|
Series: | Frontiers in Cellular and Infection Microbiology |
Subjects: | |
Online Access: | https://www.frontiersin.org/article/10.3389/fcimb.2020.00446/full |
Similar Items
-
Desferrioxamine Supports Metabolic Function in Primary Human Macrophages Infected With Mycobacterium tuberculosis
by: James Joseph Phelan, et al.
Published: (2020-05-01) -
The Warburg Effect Occurs Rapidly in Stimulated Human Adult but Not Umbilical Cord Blood Derived Macrophages
by: Cilian Ó Maoldomhnaigh, et al.
Published: (2021-04-01) -
Lactate Alters Metabolism in Human Macrophages and Improves Their Ability to Kill Mycobacterium tuberculosis
by: Cilian Ó Maoldomhnaigh, et al.
Published: (2021-10-01) -
Targeting Glycolysis in Macrophages Confers Protection Against Pancreatic Ductal Adenocarcinoma
by: Hweixian Leong Penny, et al.
Published: (2021-06-01) -
Metabolic Modulation in Macrophage Effector Function
by: Ciana Diskin, et al.
Published: (2018-02-01)