Thymoquinone Promotes Pancreatic Cancer Cell Death and Reduction of Tumor Size through Combined Inhibition of Histone Deacetylation and Induction of Histone Acetylation

Thymoquinone Promotes Pancreatic Cancer Cell Death and Reduction of Tumor Size through Combined Inhibition of Histone Deacetylation and Induction of Histone Acetylation

Pancreatic ductal adenocarcinoma (PDAC) is virtually therapy-resistant. As noninvasive lesions progress to malignancy, the precursor period provides a window for cancer therapies that can interfere with neoplastic progression. Thymoquinone (Tq), a major bioactive component of essential oil from Nige...

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Bibliographic Details
Main Authors: Daniel Relles, Galina I. Chipitsyna, Qiaoke Gong, Charles J. Yeo, Hwyda A. Arafat
Format: Article
Language:English
Published: Hindawi Limited 2016-01-01
Series:Advances in Preventive Medicine
Online Access:http://dx.doi.org/10.1155/2016/1407840

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