Blockade of ARHGAP11A reverses malignant progress via inactivating Rac1B in hepatocellular carcinoma

Blockade of ARHGAP11A reverses malignant progress via inactivating Rac1B in hepatocellular carcinoma

Abstract Background The molecular signaling events involving in high malignancy and poor prognosis of hepatocellular carcinoma (HCC) are extremely complicated. Blockade of currently known targets has not yet led to successful clinical outcome. More understanding about the regulatory mechanisms in HC...

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Bibliographic Details
Main Authors: Bin Dai, Xuan Zhang, Runze Shang, Jianlin Wang, Xisheng Yang, Hong Zhang, Qi Liu, Desheng Wang, Lin Wang, Kefeng Dou
Format: Article
Language:English
Published: BMC 2018-12-01
Series:Cell Communication and Signaling
Subjects:
ARHGAP11A
Hepatocellular carcinoma
EMT
Metastasis
Rac1B
Online Access:http://link.springer.com/article/10.1186/s12964-018-0312-4

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