Determination of voriconazole and its N-oxide in human plasma by LC-MS/MS and its clinical application
Objective To develop liquid chromatography-tandem mass spectrometry (LC-MS/MS) for the content determination of voriconazole (VRCZ) and its N-oxide (VNO) in human plasma, and to apply it to clinical samples. Methods Ketoconazole was used as the internal standard (IS). The plasma samples were treated...
Main Authors: | , , , , |
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Format: | Article |
Language: | zho |
Published: |
Editorial Office of Journal of Third Military Medical University
2019-08-01
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Series: | Di-san junyi daxue xuebao |
Subjects: | |
Online Access: | http://aammt.tmmu.edu.cn/Upload/rhtml/201902067.htm |