MiR-23a facilitates the replication of HSV-1 through the suppression of interferon regulatory factor 1.

MicroRNAs (miRNAs) are small, non-coding RNAs that negatively regulate gene expression. It has been reported that miRNAs are involved in host-virus interaction, but evidence that cellular miRNAs promote virus replication has been limited. Here, we found that miR-23a promoted the replication of human...

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Bibliographic Details
Main Authors: Jing Ru, Huahui Sun, Hongxia Fan, Chunmei Wang, Yixuan Li, Min Liu, Hua Tang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4252059?pdf=render