Immunohistochemistry is the method of choice in the differential diagnosis of neoplastic pleurisies of unknown etiology

• Main Authors: O. V. Ivanov, V. N. Klimenko, V. I. Novik, G. V. Nikolaev
• Format: Article
• Language: Russian
• Published: Academician I.P. Pavlov First St. Petersburg State Medical University 2016-06-01
• Series: Učenye Zapiski Sankt-Peterburgskogo Gosudarstvennogo Medicinskogo Universiteta im. Akad. I.P. Pavlova
• Subjects: tumor pleurisies; immunocytochemistry; differential diagnosis; the method of choice
• Online Access: https://www.sci-notes.ru/jour/article/view/330

The study included 61 patients with exudative neoplastic pleurisy of unknown primary localization. All patients underwent immunocytochemical study of pleural exudate to determine the etiology of effusion. Immunocytochemistry of 55 patients (90 %) of 61 ones was effective. The reason of exudation was both primary tumors — lung cancer (22), pleural mesothelioma (4) and pleural metastases of tumors of other localization - cancers of ovaries (9), breast (4), kidney (3), uterine body (2) , malignant lymphoma (2), colon (2), pancreas (2), thyroid gland (2), stomach (1), prostate (1), vagina (1). Immunocytochemical study of pleural effusions is the method of choice for the differential diagnosis of neoplastic pleurisies of unknown etiology.