Beta-estradiol attenuates hypoxic pulmonary hypertension by stabilizing the expression of p27<sup>kip1 </sup>in rats
<p>Abstract</p> <p>Background</p> <p>Pulmonary vascular structure remodeling (PVSR) is a hallmark of pulmonary hypertension. P27<sup>kip1</sup>, one of critical cyclin-dependent kinase inhibitors, has been shown to mediate anti-proliferation effects on vario...
Main Authors: | , , , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2010-12-01
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Series: | Respiratory Research |
Online Access: | http://respiratory-research.com/content/11/1/182 |