Beta-estradiol attenuates hypoxic pulmonary hypertension by stabilizing the expression of p27<sup>kip1 </sup>in rats

<p>Abstract</p> <p>Background</p> <p>Pulmonary vascular structure remodeling (PVSR) is a hallmark of pulmonary hypertension. P27<sup>kip1</sup>, one of critical cyclin-dependent kinase inhibitors, has been shown to mediate anti-proliferation effects on vario...

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Main Authors: Niu Wen, Zhao Peng-Tao, Dong Ming-Qing, Dong Hai-Ying, Wang Yan-Xia, Xu Min, Zhang Bo, Wang Jing, Liu Yi, Luo Ying, Xu Dun-Quan, Liu Man-Ling, Gao Yu-Qi, Li Zhi-Chao
Format: Article
Language:English
Published: BMC 2010-12-01
Series:Respiratory Research
Online Access:http://respiratory-research.com/content/11/1/182