<i>Usp22</i> Overexpression Leads to Aberrant Signal Transduction of Cancer-Related Pathways but Is Not Sufficient to Drive Tumor Formation in Mice

<i>Usp22</i> Overexpression Leads to Aberrant Signal Transduction of Cancer-Related Pathways but Is Not Sufficient to Drive Tumor Formation in Mice

<i>Usp22</i> overexpression is observed in several human cancers and is correlated with poor patient outcomes. The molecular basis underlying this correlation is not clear. <i>Usp22</i> is the catalytic subunit of the deubiquitylation module in the SAGA histone-modifying comp...

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Bibliographic Details
Main Authors: Xianghong Kuang, Michael J. McAndrew, Lisa Maria Mustachio, Ying-Jiun C. Chen, Boyko S. Atanassov, Kevin Lin, Yue Lu, Jianjun Shen, Andrew Salinger, Timothy Macatee, Sharon Y. R. Dent, Evangelia Koutelou
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Cancers
Subjects:
mammary gland epithelial cells
mouse
SAGA
<i>Usp22</i> overexpression
migration
PI3K-AKT
Online Access:https://www.mdpi.com/2072-6694/13/17/4276

Internet

https://www.mdpi.com/2072-6694/13/17/4276

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