Overcoming the inhibitory microenvironment surrounding oligodendrocyte progenitor cells following experimental demyelination

Demyelination results in impairments in oligodendrocyte progenitor cell recruitment. Here the authors identify sulfatase 1/2 as a potential modulator of myelination by modulating the microenvironment around oligodendrocyte progenitor cells.

Bibliographic Details
Main Authors: Darpan Saraswat, Hani J. Shayya, Jessie J. Polanco, Ajai Tripathi, R. Ross Welliver, Suyog U. Pol, Richard A. Seidman, Jacqueline E. Broome, Melanie A. O’Bara, Toin H. van Kuppervelt, Joanna J. Phillips, Ranjan Dutta, Fraser J. Sim
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-22263-4
Description
Summary:Demyelination results in impairments in oligodendrocyte progenitor cell recruitment. Here the authors identify sulfatase 1/2 as a potential modulator of myelination by modulating the microenvironment around oligodendrocyte progenitor cells.
ISSN:2041-1723