Towards Biohybrid Lung: Induced Pluripotent Stem Cell Derived Endothelial Cells as Clinically Relevant Cell Source for Biologization

Towards Biohybrid Lung: Induced Pluripotent Stem Cell Derived Endothelial Cells as Clinically Relevant Cell Source for Biologization

In order to provide an alternative treatment option to lung transplantation for patients with end-stage lung disease, we aim for the development of an implantable biohybrid lung (BHL), based on hollow fiber membrane (HFM) technology used in extracorporeal membrane oxygenators. Complete hemocompatibi...

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Bibliographic Details
Main Authors: Michael Pflaum, Julia Dahlmann, Lena Engels, Hossein Naghilouy-Hidaji, Denise Adam, Janina Zöllner, Annette Otto, Sabrina Schmeckebier, Ulrich Martin, Axel Haverich, Ruth Olmer, Bettina Wiegmann
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Micromachines
Subjects:
biohybrid lung
induced pluripotent stem cells
endothelialization
hemocompatibility
EC activation
membrane oxygenator
Online Access:https://www.mdpi.com/2072-666X/12/8/981

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https://www.mdpi.com/2072-666X/12/8/981

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