Autophagy protects against oxaliplatin-induced cell death via ER stress and ROS in Caco-2 cells.
Oxaliplatin is included in a number of effective combination regimens used as first and subsequent lines of therapy for metastatic colorectal cancer. Accumulating evidence indicates that autophagy plays a significant role in response to cancer therapy. However, the role of autophagy in oxaliplatin-i...
Main Authors: | Yan Shi, Bin Tang, Pei-Wu Yu, Bo Tang, Ying-Xue Hao, Xiao Lei, Hua-Xing Luo, Dong-Zhu Zeng |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2012-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3511352?pdf=render |
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