A simple immunohistochemical bio-profile incorporating Bcl2 curbs those cases of invasive breast carcinoma for which an Oncotype Dx characterization is needed.

A simple immunohistochemical bio-profile incorporating Bcl2 curbs those cases of invasive breast carcinoma for which an Oncotype Dx characterization is needed.

<h4>Aim</h4>Our goal has been to evaluate the importance that the incorporation of Bcl2 in the ER/PGR/Her2/Ki67 bio-profile can have as predictor of the Oncotype Dx categories.<h4>Material and methods</h4>156 consecutive cases of HR+/Her2- pN0/1 primary breast carcinoma were...

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Bibliographic Details
Main Authors: Claudio Ceccarelli, Antonio De Leo, Pasquale Chieco, Claudio Zamagni, Alice Zamagni, Daniela Rubino, Mario Taffurelli, Donatella Santini
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0217937

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