Calcitonin inhibits SDCP-induced osteoclast apoptosis and increases its efficacy in a rat model of osteoporosis.

Calcitonin inhibits SDCP-induced osteoclast apoptosis and increases its efficacy in a rat model of osteoporosis.

INTRODUCTION: Treatment for osteoporosis commonly includes the use of bisphosphonates. Serious side effects of these drugs are caused by the inhibition of bone resorption as a result of osteoclast apoptosis. Treatment using calcitonin along with bisphosphonates overcomes these side-effects in some p...

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Main Authors: Yi-Jie Kuo, Fon-Yih Tsuang, Jui-Sheng Sun, Chi-Hung Lin, Chia-Hsien Chen, Jia-Ying Li, Yi-Chian Huang, Wei-Yu Chen, Chin-Bin Yeh, Jia-Fwu Shyu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3391248?pdf=render

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