Metabolic Disorders in Patients with HIV

Metabolic Disorders in Patients with HIV

Human Immunodeficiency Virus (HIV) infection and subsequent antiretroviral therapy (ART) are known to be related to different metabolic disorders. Although ART decreased HIV-associated mortality and morbidity, mortality rates in patients with HIV and ART are 3 to 15 higher than those in the general...

Full description

Bibliographic Details
Main Authors: Radu Florentina, Jipa Raluca Elena, Rusu Emilia, Cursaru Raluca, Drăguţ Ramona, Stegaru Daniela, Gheorghiţă Andra Gabriela, Radulian Gabriela
Format: Article
Language:English
Published: Sciendo 2016-12-01
Series:Romanian Journal of Diabetes Nutrition and Metabolic Diseases
Subjects:
insulin resistance
metabolic disorders
dyslipidemia
diabetes
Online Access:http://www.degruyter.com/view/j/rjdnmd.2016.23.issue-4/rjdnmd-2016-0046/rjdnmd-2016-0046.xml?format=INT
Description
Summary:Human Immunodeficiency Virus (HIV) infection and subsequent antiretroviral therapy (ART) are known to be related to different metabolic disorders. Although ART decreased HIV-associated mortality and morbidity, mortality rates in patients with HIV and ART are 3 to 15 higher than those in the general population. More than 50% of the mortality is due to diseases like: diabetes mellitus (DM), hypertension, cardiovascular diseases (CVD), chronic renal disease and complications following bone fractures. In patients with HIV the metabolic disorders are mainly caused by mithocondrial toxicity, a side effect of ART, and they are represented by: dyslipidemia, lipoatrophy, insulin resistance and diabetes mellitus.
ISSN:2284-6417

Similar Items