Lipid profile in psoriasis patients

Ramesh Marne Bhat, Hyacinth Peter PintoDepartment of Dermatology, Fr Muller Medical College, Kankanady, Mangalore, IndiaObjective: To compare the lipid profile values of psoriatic patients with those of age and sex-matched nonpsoriatic controls, while providing a review of the literature.Methods: A...

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Main Authors: Bhat RM, Pinto HP
Format: Article
Language:English
Published: Dove Medical Press 2012-11-01
Series:Psoriasis : Targets and Therapy
Online Access:http://www.dovepress.com/lipid-profile-in-psoriasis-patients-a11492
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spelling doaj-83da7b2a58084365bdc60d039acaa8fc2020-11-24T23:05:12ZengDove Medical PressPsoriasis : Targets and Therapy2230-326X2012-11-012012default7780Lipid profile in psoriasis patientsBhat RMPinto HPRamesh Marne Bhat, Hyacinth Peter PintoDepartment of Dermatology, Fr Muller Medical College, Kankanady, Mangalore, IndiaObjective: To compare the lipid profile values of psoriatic patients with those of age and sex-matched nonpsoriatic controls, while providing a review of the literature.Methods: A total of 20 consecutive patients with chronic plaque psoriasis (18 males and two females) and 20 age- and sex-matched healthy individuals without psoriasis were included as controls in this study. Serum levels of cholesterol, triglycerides, low-density lipoprotein, and high-density lipoprotein were measured after 12 hours of overnight fasting.Results: The serum levels of total and low-density lipoprotein cholesterol were found to be higher in both the psoriatic and the control group; thus there were no statistically significant difference between both groups of individuals.Conclusion: Psoriasis is now emerging as an important systemic disease associated with various comorbid conditions that include diabetes, hypertension, and an abnormal lipid profile as reviewed by various studies. Such comorbid conditions that are linked with psoriasis have been associated with increasing rates of morbidity and mortality. Our study indicated that there was an increase in total and low-density lipoprotein cholesterol in both patients and controls, indicating that there is an overall increase of these levels in the general population. Therefore, it is important that the lipid profiles of these patients continue to be studied.Keywords: psoriasis, lipid profile, serum cholesterol, serum triglycerides, serum LDL, serum HDLhttp://www.dovepress.com/lipid-profile-in-psoriasis-patients-a11492
collection DOAJ
language English
format Article
sources DOAJ
author Bhat RM
Pinto HP
spellingShingle Bhat RM
Pinto HP
Lipid profile in psoriasis patients
Psoriasis : Targets and Therapy
author_facet Bhat RM
Pinto HP
author_sort Bhat RM
title Lipid profile in psoriasis patients
title_short Lipid profile in psoriasis patients
title_full Lipid profile in psoriasis patients
title_fullStr Lipid profile in psoriasis patients
title_full_unstemmed Lipid profile in psoriasis patients
title_sort lipid profile in psoriasis patients
publisher Dove Medical Press
series Psoriasis : Targets and Therapy
issn 2230-326X
publishDate 2012-11-01
description Ramesh Marne Bhat, Hyacinth Peter PintoDepartment of Dermatology, Fr Muller Medical College, Kankanady, Mangalore, IndiaObjective: To compare the lipid profile values of psoriatic patients with those of age and sex-matched nonpsoriatic controls, while providing a review of the literature.Methods: A total of 20 consecutive patients with chronic plaque psoriasis (18 males and two females) and 20 age- and sex-matched healthy individuals without psoriasis were included as controls in this study. Serum levels of cholesterol, triglycerides, low-density lipoprotein, and high-density lipoprotein were measured after 12 hours of overnight fasting.Results: The serum levels of total and low-density lipoprotein cholesterol were found to be higher in both the psoriatic and the control group; thus there were no statistically significant difference between both groups of individuals.Conclusion: Psoriasis is now emerging as an important systemic disease associated with various comorbid conditions that include diabetes, hypertension, and an abnormal lipid profile as reviewed by various studies. Such comorbid conditions that are linked with psoriasis have been associated with increasing rates of morbidity and mortality. Our study indicated that there was an increase in total and low-density lipoprotein cholesterol in both patients and controls, indicating that there is an overall increase of these levels in the general population. Therefore, it is important that the lipid profiles of these patients continue to be studied.Keywords: psoriasis, lipid profile, serum cholesterol, serum triglycerides, serum LDL, serum HDL
url http://www.dovepress.com/lipid-profile-in-psoriasis-patients-a11492
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