Midkine Is a Potential Therapeutic Target of Tumorigenesis, Angiogenesis, and Metastasis in Non-Small Cell Lung Cancer

Midkine Is a Potential Therapeutic Target of Tumorigenesis, Angiogenesis, and Metastasis in Non-Small Cell Lung Cancer

Hypoxia-inducible factors (HIFs) induced by reduced O<sub>2</sub> availability activate the transcription of target genes encoding proteins that play important roles in communication between cancer and stromal cells. Cancer cells were incubated under hypoxic conditions: H1299, A549 (NSCL...

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Bibliographic Details
Main Authors: Dong Hoon Shin, Jeong Yeon Jo, Sun Ha Kim, Minyoung Choi, Chungyong Han, Beom K. Choi, Sang Soo Kim
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Cancers
Subjects:
midkine
tumor progression
metastasis
angiogenesi
NSCLC
Online Access:https://www.mdpi.com/2072-6694/12/9/2402

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