A Preliminary Study of Microsatellite Instability Analysis in Different Genotypes of P53 Codon 72 in Breast Invasive Ductal Carcinomas

A Preliminary Study of Microsatellite Instability Analysis in Different Genotypes of P53 Codon 72 in Breast Invasive Ductal Carcinomas

Background:The polymorphic variants at codon 72 of the p53 gene, encoding either proline or arginine at residue 72,produce marked change in the structure of p53.From the evidence that the DNAmismatch repair system and p53 interact to maintain genomic integrity, we hypothesized that the codon 72 vari...

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Bibliographic Details
Main Authors: Mansour Salehi, Mohammad Rabbani, Mehdi Nikbahkt Dastjerdi, Masoumeh Faghani
Format: Article
Language:English
Published: Iran University of Medical Sciences 2009-08-01
Series:Medical Journal of The Islamic Republic of Iran
Subjects:
Microsatellite Instability
Polymorphism
P53
Breast Invasive Ductal Carcinoma
Online Access:http://mjiri.tums.ac.ir/browse.php?a_code=A-10-1-65&slc_lang=en&sid=1

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