Inactivation of Fam20C in cells expressing type I collagen causes periodontal disease in mice.

Inactivation of Fam20C in cells expressing type I collagen causes periodontal disease in mice.

FAM20C is a kinase that phosphorylates secretory proteins. Previous studies have shown that FAM20C plays an essential role in the formation and mineralization of bone, dentin and enamel. The present study analyzed the loss-of-function effects of FAM20C on the health of mouse periodontal tissues.By c...

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Bibliographic Details
Main Authors: Peihong Liu, Hua Zhang, Chao Liu, Xiaofang Wang, Li Chen, Chunlin Qin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4257665?pdf=render

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