The Proinflammatory Cytokine IL-36γ Is a Global Discriminator of Harmless Microbes and Invasive Pathogens within Epithelial Tissues

The Proinflammatory Cytokine IL-36γ Is a Global Discriminator of Harmless Microbes and Invasive Pathogens within Epithelial Tissues

Summary: Epithelial tissues represent vital interfaces between organisms and their environment. As they are constantly exposed to harmful pathogens, innocuous commensals, and environmental microbes, it is essential they sense and elicit appropriate responses toward these different types of microbes....

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Bibliographic Details
Main Authors: Thomas Macleod, Joseph S. Ainscough, Christina Hesse, Sebastian Konzok, Armin Braun, Anna-Lena Buhl, Joerg Wenzel, Paul Bowyer, Yutaka Terao, Sarah Herrick, Miriam Wittmann, Martin Stacey
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:Cell Reports
Subjects:
epithelial immunity
interleukin-36
IL-36
cytokines
alarmins
pathogen discrimination
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124720315047

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