GNE is involved in the early development of skeletal and cardiac muscle.

GNE is involved in the early development of skeletal and cardiac muscle.

UDP-N-acetylglucosamine 2 epimerase/N-acetylmannosamime kinase (GNE) is a bifunctional enzyme which catalyzes the two key sequential steps in the biosynthetic pathway of sialic acid, the most abundant terminal monosaccharide on glycoconjugates of eukaryotic cells. GNE knock out (GNE KO) mice are emb...

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Bibliographic Details
Main Authors: Irit Milman Krentsis, Ilan Sela, Rachel Eiges, Véronique Blanchard, Markus Berger, Michal Becker Cohen, Stella Mitrani-Rosenbaum
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3123316?pdf=render

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