Closing the Gap: Mechanisms of Epithelial Fusion During Optic Fissure Closure

A key embryonic process that occurs early in ocular development is optic fissure closure (OFC). This fusion process closes the ventral optic fissure and completes the circumferential continuity of the 3-dimensional eye. It is defined by the coming together and fusion of opposing neuroepithelia along...

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Bibliographic Details
Main Authors: Brian Ho Ching Chan, Mariya Moosajee, Joe Rainger
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2020.620774/full