Development of a novel in silico docking simulation model for the fine HIV-1 cytotoxic T lymphocyte epitope mapping.
INTRODUCTION: Class I HLA's polymorphism has hampered CTL epitope mapping with laborious experiments. Objectives are 1) to evaluate the novel in silico model in predicting previously reported epitopes in comparison with existing program, and 2) to apply the model to predict optimal epitopes wit...
Main Authors: | Masahiko Mori, Kei Matsuki, Tomoyuki Maekawa, Mari Tanaka, Busarawan Sriwanthana, Masaru Yokoyama, Koya Ariyoshi |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2012-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3407191?pdf=render |
Similar Items
-
The effect of HLA polymorphisms on the recognition of Gag epitopes in HIV-1 CRF01_AE infection.
by: Busarawan Sriwanthana, et al.
Published: (2012-01-01) -
Unique CRF01_AE Gag CTL epitopes associated with lower HIV-viral load and delayed disease progression in a cohort of HIV-infected Thais.
by: Masahiko Mori, et al.
Published: (2011-01-01) -
A docking-based method for in silico epitope determination
by: Tahir, Shifa
Published: (2018) -
In silico inference of immunological relationship between protein antigens based on their cytotoxic T-lymphocyte epitope repertoires
by: Smidt, Werner
Published: (2013) -
In silico discovery of novel cytotoxic T-lymphocyte epitopes in
the HIV-1 Pol region in response to antiretroviral resistance
mutations
by: Smidt, Werner
Published: (2015)