Pro-apoptotic activity against cancer stem cells differs between different parts of sweet sorghum

Pro-apoptotic activity against cancer stem cells differs between different parts of sweet sorghum

The extracts from sweet sorghum stalk were previously shown to eliminate human colon cancer stem cells (CCSC) in a partial p53-dependent fashion. However, the underlying mechanisms remain unknown. In this study, we transfected CCSC with shRNA against p53 and treated with sweet sorghum phenolics extr...

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Bibliographic Details
Main Authors: Aaron R. Massey, Lavanya Reddivari, Sridhar Radhakrishnan, Venkata Charepalli, Eranda Karunathilake Kurundu Hewage, Vadde Ramakrishna, Jairam K.P. Vanamala
Format: Article
Language:English
Published: Elsevier 2016-05-01
Series:Journal of Functional Foods
Subjects:
Sorghum bicolor
Sweet sorghum
Biorefinery
Apoptosis
Colon cancer stem cell
Online Access:http://www.sciencedirect.com/science/article/pii/S175646461630024X

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