Biparental contributions of the H2A.B histone variant control embryonic development in mice.

Biparental contributions of the H2A.B histone variant control embryonic development in mice.

Histone variants expand chromatin functions in eukaryote genomes. H2A.B genes are testis-expressed short histone H2A variants that arose in placental mammals. Their biological functions remain largely unknown. To investigate their function, we generated a knockout (KO) model that disrupts all 3 H2A....

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Bibliographic Details
Main Authors: Antoine Molaro, Anna J Wood, Derek Janssens, Selina M Kindelay, Michael T Eickbush, Steven Wu, Priti Singh, Charles H Muller, Steven Henikoff, Harmit S Malik
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-12-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.3001001

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