Effects of Osteoglycin (OGN) on treating senile osteoporosis by regulating MSCs

Effects of Osteoglycin (OGN) on treating senile osteoporosis by regulating MSCs

Abstract Background Significant amount of bone mass is lost during the process of aging due to an imbalance between osteoblast-mediated bone formation and osteoclast-mediated bone resorption in bone marrow microenvironment, which leads to net bone loss in the aging population, resulting in the patho...

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Bibliographic Details
Main Authors: Xia Chen, Junsong Chen, Dongliang Xu, Shuangxia Zhao, Huaidong Song, Yongde Peng
Format: Article
Language:English
Published: BMC 2017-10-01
Series:BMC Musculoskeletal Disorders
Subjects:
Osteoglycin
Peroxisome proliferators-activated receptor-γ 2
Senile osteoporosis
Adipogenesis
Osteoblastogenesis
Mesenchymal stromal cells
Online Access:http://link.springer.com/article/10.1186/s12891-017-1779-7

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http://link.springer.com/article/10.1186/s12891-017-1779-7

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