Visual Evoked Responses In Neurotuberculosis

• Main Authors: Thacker AK, Jaiswal SC, Upadhyay BK, Kankane A
• Format: Article
• Language: English
• Published: Wolters Kluwer Medknow Publications 2002-01-01
• Series: Annals of Indian Academy of Neurology
• Online Access: http://www.annalsofian.org/article.asp?issn=0972-2327;year=2002;volume=5;issue=2;spage=153;epage=157;aulast=Thacker;type=0

Thirty one patients with neuro-tuberculosis were subjected to pattern reversal visual evoked response (VER) studies. Eighteen patients had lone tubercular meningitis (TbM), while thirteen had additional complications (TbM+). VER abnormalities were recorded in thirteen patients (41.9%) as against abnormal clinical neuro-ophthalmologic assessment of 5 (16.1%). Compared to control values, mean VER latencies, inter-ocular. P 100 latency difference and amplitude of the reponses among patients were altered significantly, with no difference in the VER dispersion. The VER parameters of the patients with TbM and those with TbM+ were similar but for greater inter-ocular latency difference in the latter. The VER findings in patients with neurotuberculosis suggest asymmetric anterior visual pathways abnormalities predominantly of demyelinating in nature with asymmetry being more marked in patients with TbM+ with complications.