Relationship between localization on cellular membranes and cytotoxicity of Vibrio vulnificus hemolysin.

Relationship between localization on cellular membranes and cytotoxicity of Vibrio vulnificus hemolysin.

Vibrio vulnificus secretes a hemolysin/cytolysin (VVH) that induces cytolysis in target cells. A detergent resistant membrane domain (DRM) fraction of the cells after sucrose gradient centrifugation includes cholesterol-rich membrane microdomains which have been called "lipid rafts". It wa...

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Bibliographic Details
Main Authors: Hiroyuki Sugiyama, Takashige Kashimoto, Shunji Ueno, Hayato Ehara, Toshio Kodama, Tetsuya Iida, Nobuyuki Susa
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3197612?pdf=render

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