Bruchpilot and Synaptotagmin collaborate to drive rapid glutamate release and active zone differentiation

Bruchpilot and Synaptotagmin collaborate to drive rapid glutamate release and active zone differentiation

The active zone (AZ) protein Bruchpilot (Brp) is essential for rapid glutamate release at Drosophila melanogaster neuromuscular junctions (NMJs). Quantal time course and measurements of action potential-waveform suggest that presynaptic fusion mechanisms are altered in brp null mutants (brp69). This...

Full description

Bibliographic Details
Main Authors: Mila M Paul, Martin ePauli, Nadine eEhmann, Stefan eHallermann, Markus eSauer, Robert J Kittel, Manfred eHeckmann
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-02-01
Series:Frontiers in Cellular Neuroscience
Subjects:
active Zone
neurotransmitter release
presynaptic differentiation
synaptotagmin
dSTORM
Bruchpilot
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2015.00029/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fncel.2015.00029/full

Similar Items