BMP signaling in astrocytes downregulates EGFR to modulate survival and maturation.

Astrocytes constitute a major cell population in the brain with a myriad of essential functions, yet we know remarkably little about the signaling pathways and mechanisms that direct astrocyte maturation. To explore the signals regulating astrocyte development, we prospectively purified and cultured...

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Bibliographic Details
Main Authors: Anja R Scholze, Lynette C Foo, Sara Mulinyawe, Ben A Barres
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4201562?pdf=render