Synthesis and exploration of a novel chlorobenzylated 2-aminothiazole-phenyltriazole hybrid as migratory inhibitor of B16F10 in melanoma cells

Synthesis and exploration of a novel chlorobenzylated 2-aminothiazole-phenyltriazole hybrid as migratory inhibitor of B16F10 in melanoma cells

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In the study presented here, a novel chlorobenzylated bi-heterocyclic hybrid molecule (7) was synthesized and its structural confirmation was carried out by IR, 1H-NMR, 13C-NMR and CHN analysis data. This compound 7 was subjected to biological study with B16F10 mouse melanoma cells. The anti-prolife...

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Bibliographic Details
Main Authors: Muhammad Athar Abbasi, Seon-Mi Yu, Aziz-ur-Rehman, Sabahat Zahra Siddiqui, Song Ja Kim, Hussain Raza, Mubashir Hassan, Abdul Rehman Sadiq Butt, Syed Adnan Ali Shah, Sung-Yum Seo
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:Toxicology Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2214750018307455
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