Synthesis and exploration of a novel chlorobenzylated 2-aminothiazole-phenyltriazole hybrid as migratory inhibitor of B16F10 in melanoma cells
In the study presented here, a novel chlorobenzylated bi-heterocyclic hybrid molecule (7) was synthesized and its structural confirmation was carried out by IR, 1H-NMR, 13C-NMR and CHN analysis data. This compound 7 was subjected to biological study with B16F10 mouse melanoma cells. The anti-prolife...
Main Authors: | Muhammad Athar Abbasi, Seon-Mi Yu, Aziz-ur-Rehman, Sabahat Zahra Siddiqui, Song Ja Kim, Hussain Raza, Mubashir Hassan, Abdul Rehman Sadiq Butt, Syed Adnan Ali Shah, Sung-Yum Seo |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2019-01-01
|
Series: | Toxicology Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2214750018307455 |
Similar Items
-
Synthesis and exploration of a novel chlorobenzylated 2-aminothiazole-phenyltriazole hybrid as migratory inhibitor of B16F10 in melanoma cells
by: Athar Abbasi, M., et al.
Published: (2019) -
Synthesis, enzyme inhibitory kinetics mechanism and computational study of N-(4-methoxyphenethyl)-N-(substituted)-4-methylbenzenesulfonamides as novel therapeutic agents for Alzheimer’s disease
by: Muhammad Athar Abbasi, et al.
Published: (2018-06-01) -
3-(3-Chlorobenzyl)-1H-isochromen-1-one
by: Zdenka Padelkova, et al.
Published: (2008-10-01) -
Structure-activity relationship and in silico study of unique bi-heterocycles: 5-[(2-amino-1,3-thiazol-4-yl)methyl]-1,3,4-oxadiazole-2-thiol derivatives
by: Abbasi Muhammad Athar, et al.
Published: (2019-01-01) -
Synthesis of Bi-heterocyclic Sulfonamides as Tyrosinase Inhibitors: Lineweaver–Burk Plot Evaluation and Computational Ascriptions
by: Muhammad Athar Abbasi, et al.
Published: (2020-06-01)