Protective Effects of Polydatin on Septic Lung Injury in Mice via Upregulation of HO-1

Protective Effects of Polydatin on Septic Lung Injury in Mice via Upregulation of HO-1

The present study was carried out to investigate the effects and mechanisms of polydatin (PD) in septic mice. The model of cecal ligation and puncture (CLP-)induced sepsis was employed. Pretreatment of mice with PD (15, 45, and 100 mg/kg) dose-dependently reduced sepsis-induced mortality and lung in...

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Bibliographic Details
Main Authors:	Xiao-hui Li, Xia Gong, Li Zhang, Rong Jiang, Hong-zhong Li, Meng-jiao Wu, Jing-yuan Wan
Format:	Article
Language:	English
Published:	Hindawi Limited 2013-01-01
Series:	Mediators of Inflammation
Online Access:	http://dx.doi.org/10.1155/2013/354087

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