Interferon-γ enhances the therapeutic effect of mesenchymal stem cells on experimental renal fibrosis

Interferon-γ enhances the therapeutic effect of mesenchymal stem cells on experimental renal fibrosis

Abstract Mesenchymal stem cells (MSCs) administered for therapeutic purposes can be activated by interferon-γ (IFN-γ) secreted from natural killer cells in injured tissues and exert anti-inflammatory effects. These processes require a substantial period of time, leading to a delayed onset of MSCs’ t...

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Bibliographic Details
Main Authors:	Ryo Kanai, Ayumu Nakashima, Shigehiro Doi, Tomoe Kimura, Ken Yoshida, Satoshi Maeda, Naoki Ishiuchi, Yumi Yamada, Takeshi Ike, Toshiki Doi, Yukio Kato, Takao Masaki
Format:	Article
Language:	English
Published:	Nature Publishing Group 2021-01-01
Series:	Scientific Reports
Online Access:	https://doi.org/10.1038/s41598-020-79664-6

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