Prasugrel, a new medicine for preventing blockages in the arteries
Prasugrel {systematic name: 5-[(2-cyclopropylcarbonyl)(2-fluorophenyl)methyl]-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl acetate}, C20H20FNO3S, is a new third-generation thienopyridine which was recently approved for clinical use as a more potent blocker of the platelet P2Y12 receptor than clopidog...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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International Union of Crystallography
2010-06-01
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| Series: | Acta Crystallographica Section E |
| Online Access: | http://scripts.iucr.org/cgi-bin/paper?S1600536810017095 |
| Summary: | Prasugrel {systematic name: 5-[(2-cyclopropylcarbonyl)(2-fluorophenyl)methyl]-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl acetate}, C20H20FNO3S, is a new third-generation thienopyridine which was recently approved for clinical use as a more potent blocker of the platelet P2Y12 receptor than clopidogrel, which was previously used for this purpose. The molecule features a tetrahydrothienopyridine system with the tetrahydropyridine ring showing a half-chair conformation; the dihedral angle formed by the the planes of the benzene and thiophene rings is 83.17 (3)°. |
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| ISSN: | 1600-5368 |