The protein translation machinery is expressed for maximal efficiency in Escherichia coli
The protein translation machinery is the most expensive cellular subsystem in fast growing bacteria. Providing a detailed mechanistic model for this complex system, the authors show that the translation machinery components are expressed such that their combined cost to the cell is minimal.
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| Format: | Article |
| Language: | English |
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Nature Publishing Group
2020-10-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-020-18948-x |
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doaj-8368f1712aa4497b9baaa3f01b8450b4 |
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Article |
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doaj-8368f1712aa4497b9baaa3f01b8450b42021-05-11T08:57:41ZengNature Publishing GroupNature Communications2041-17232020-10-0111111010.1038/s41467-020-18948-xThe protein translation machinery is expressed for maximal efficiency in Escherichia coliXiao-Pan Hu0Hugo Dourado1Peter Schubert2Martin J. Lercher3Institute for Computer Science and Department of Biology, Heinrich Heine UniversityInstitute for Computer Science and Department of Biology, Heinrich Heine UniversityInstitute for Computer Science and Department of Biology, Heinrich Heine UniversityInstitute for Computer Science and Department of Biology, Heinrich Heine UniversityThe protein translation machinery is the most expensive cellular subsystem in fast growing bacteria. Providing a detailed mechanistic model for this complex system, the authors show that the translation machinery components are expressed such that their combined cost to the cell is minimal.https://doi.org/10.1038/s41467-020-18948-x |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Xiao-Pan Hu Hugo Dourado Peter Schubert Martin J. Lercher |
| spellingShingle |
Xiao-Pan Hu Hugo Dourado Peter Schubert Martin J. Lercher The protein translation machinery is expressed for maximal efficiency in Escherichia coli Nature Communications |
| author_facet |
Xiao-Pan Hu Hugo Dourado Peter Schubert Martin J. Lercher |
| author_sort |
Xiao-Pan Hu |
| title |
The protein translation machinery is expressed for maximal efficiency in Escherichia coli |
| title_short |
The protein translation machinery is expressed for maximal efficiency in Escherichia coli |
| title_full |
The protein translation machinery is expressed for maximal efficiency in Escherichia coli |
| title_fullStr |
The protein translation machinery is expressed for maximal efficiency in Escherichia coli |
| title_full_unstemmed |
The protein translation machinery is expressed for maximal efficiency in Escherichia coli |
| title_sort |
protein translation machinery is expressed for maximal efficiency in escherichia coli |
| publisher |
Nature Publishing Group |
| series |
Nature Communications |
| issn |
2041-1723 |
| publishDate |
2020-10-01 |
| description |
The protein translation machinery is the most expensive cellular subsystem in fast growing bacteria. Providing a detailed mechanistic model for this complex system, the authors show that the translation machinery components are expressed such that their combined cost to the cell is minimal. |
| url |
https://doi.org/10.1038/s41467-020-18948-x |
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