Donor-Derived CD123-Targeted CAR T Cell Serves as a RIC Regimen for Haploidentical Transplantation in a Patient With FUS-ERG+ AML

Donor-Derived CD123-Targeted CAR T Cell Serves as a RIC Regimen for Haploidentical Transplantation in a Patient With FUS-ERG+ AML

Background: Allogeneic hematopoietic stem cell transplantation (allo-HSCT) following chemotherapy is part of standard treatment protocol for patients with acute myeloid leukemia (AML). FUS-ERG+ AML is rare but has an extremely poor prognosis even with allo-HSCT in remission, possibly due to its a le...

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Bibliographic Details
Main Authors:	Sun Yao, Chen Jianlin, Liu Yarong, Li Botao, Wang Qinghan, Fang Hongliang, Zhang Lu, Ning Hongmei, Wang Pin, Chen Hu, Hu Liangding, Zhang Bin
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2019-12-01
Series:	Frontiers in Oncology
Subjects:	chimeric antigen receptor CD123 allogeneic hematopoietic stem cell transplantation acute myeloid leukemia cytokine release syndrome graft-vs-host disease
Online Access:	https://www.frontiersin.org/article/10.3389/fonc.2019.01358/full

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