ORF8 contributes to cytokine storm during SARS-CoV-2 infection by activating IL-17 pathway
Summary: Recently, COVID-19 caused by the novel coronavirus SARS-CoV-2 has brought great challenges to the world. More and more studies have shown that patients with severe COVID-19 may suffer from cytokine storm syndrome; however, there are few studies on its pathogenesis. Here we demonstrated that...
Main Authors: | Xiaoyuan Lin, Beibei Fu, Songna Yin, Zhifeng Li, Huawen Liu, Haiwei Zhang, Na Xing, Yu Wang, Weiwei Xue, Yan Xiong, Shanfu Zhang, Qingting Zhao, Shiyao Xu, Jing Zhang, Peihui Wang, Weiqi Nian, Xingsheng Wang, Haibo Wu |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2021-04-01
|
Series: | iScience |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2589004221002613 |
Similar Items
-
Structural insight reveals SARS-CoV-2 ORF7a as an immunomodulating factor for human CD14+ monocytes
by: Ziliang Zhou, et al.
Published: (2021-03-01) -
MicroRNA-325-3p Facilitates Immune Escape of Mycobacterium tuberculosis through Targeting LNX1 via NEK6 Accumulation to Promote Anti-Apoptotic STAT3 Signaling
by: Beibei Fu, et al.
Published: (2020-06-01) -
Characterization of the role of ICP34.5 and ORF P in the HSV-1 lifecycle
by: Karimi-Khoozani, Ali
Published: (2003) -
SARS-CoV-2 Targets by the pscRNA Profiling of ACE2, TMPRSS2 and Furin Proteases
by: Lulin Zhou, et al.
Published: (2020-11-01) - Modulation of Kinase Signaling by ORF45 during the Lytic Cycle of Kaposi's Sarcoma-Associated Herpesvirus