Nucleated Polymerisation in the Presence of Pre-Formed Seed Filaments
We revisit the classical problem of nucleated polymerisation and derive a range of exact results describing polymerisation in systems intermediate between the well-known limiting cases of a reaction starting from purely soluble material and for a reaction where no new growth nuclei are formed.
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| Format: | Article |
| Language: | English |
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MDPI AG
2011-09-01
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| Series: | International Journal of Molecular Sciences |
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| Online Access: | http://www.mdpi.com/1422-0067/12/9/5844/ |
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doaj-83642b9540f94a699d601b1dcd436af8 |
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Article |
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doaj-83642b9540f94a699d601b1dcd436af82020-11-24T20:48:01ZengMDPI AGInternational Journal of Molecular Sciences1422-00672011-09-011295844585210.3390/ijms12095844Nucleated Polymerisation in the Presence of Pre-Formed Seed FilamentsTuomas P. J. KnowlesMichele VendruscoloSamuel I. A. CohenChristopher M. DobsonWe revisit the classical problem of nucleated polymerisation and derive a range of exact results describing polymerisation in systems intermediate between the well-known limiting cases of a reaction starting from purely soluble material and for a reaction where no new growth nuclei are formed.http://www.mdpi.com/1422-0067/12/9/5844/proteinaggregationamyloid |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Tuomas P. J. Knowles Michele Vendruscolo Samuel I. A. Cohen Christopher M. Dobson |
| spellingShingle |
Tuomas P. J. Knowles Michele Vendruscolo Samuel I. A. Cohen Christopher M. Dobson Nucleated Polymerisation in the Presence of Pre-Formed Seed Filaments International Journal of Molecular Sciences protein aggregation amyloid |
| author_facet |
Tuomas P. J. Knowles Michele Vendruscolo Samuel I. A. Cohen Christopher M. Dobson |
| author_sort |
Tuomas P. J. Knowles |
| title |
Nucleated Polymerisation in the Presence of Pre-Formed Seed Filaments |
| title_short |
Nucleated Polymerisation in the Presence of Pre-Formed Seed Filaments |
| title_full |
Nucleated Polymerisation in the Presence of Pre-Formed Seed Filaments |
| title_fullStr |
Nucleated Polymerisation in the Presence of Pre-Formed Seed Filaments |
| title_full_unstemmed |
Nucleated Polymerisation in the Presence of Pre-Formed Seed Filaments |
| title_sort |
nucleated polymerisation in the presence of pre-formed seed filaments |
| publisher |
MDPI AG |
| series |
International Journal of Molecular Sciences |
| issn |
1422-0067 |
| publishDate |
2011-09-01 |
| description |
We revisit the classical problem of nucleated polymerisation and derive a range of exact results describing polymerisation in systems intermediate between the well-known limiting cases of a reaction starting from purely soluble material and for a reaction where no new growth nuclei are formed. |
| topic |
protein aggregation amyloid |
| url |
http://www.mdpi.com/1422-0067/12/9/5844/ |
| work_keys_str_mv |
AT tuomaspjknowles nucleatedpolymerisationinthepresenceofpreformedseedfilaments AT michelevendruscolo nucleatedpolymerisationinthepresenceofpreformedseedfilaments AT samueliacohen nucleatedpolymerisationinthepresenceofpreformedseedfilaments AT christophermdobson nucleatedpolymerisationinthepresenceofpreformedseedfilaments |
| _version_ |
1716809241226903552 |