DNA-Repair Gene Mutations Are Highly Prevalent in Circulating Tumour DNA from Multiple Myeloma Patients

Mutational characterisation utilising plasma (PL)-derived circulating tumour DNA (ctDNA) in multiple myeloma (MM) has been recently described. Mutational analyses of paired bone marrow (BM) MM cell DNA and ctDNA from 76 patients (<i>n</i> = 24, new diagnosis (ND), <i>n</i> =...

Full description

Bibliographic Details
Main Authors: Sridurga Mithraprabhu, Jay Hocking, Malarmathy Ramachandran, Kawa Choi, Daniela Klarica, Tiffany Khong, John Reynolds, Andrew Spencer
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:Cancers
Subjects:
RAS
Online Access:https://www.mdpi.com/2072-6694/11/7/917