Autophagy-dependent and -independent modulation of oxidative and organellar stress in the diabetic heart by glucose-lowering drugs
Abstract Autophagy is a lysosome-dependent intracellular degradative pathway, which mediates the cellular adaptation to nutrient and oxygen depletion as well as to oxidative and endoplasmic reticulum stress. The molecular mechanisms that stimulate autophagy include the activation of energy deprivati...
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| Format: | Article |
| Language: | English |
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BMC
2020-05-01
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| Series: | Cardiovascular Diabetology |
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| Online Access: | http://link.springer.com/article/10.1186/s12933-020-01041-4 |