Long-Term Administration of Neuropeptide Y in the Subcutaneous Infusion Results in Cardiac Dysfunction and Hypertrophy in Rats

Long-Term Administration of Neuropeptide Y in the Subcutaneous Infusion Results in Cardiac Dysfunction and Hypertrophy in Rats

Background/Aims: The purpose of the present study was to clarify whether chronically elevated plasma neuropeptide Y (NPY) might affect heart function and cardiac remodeling in rats. Methods: Male Wistar rats were administered NPY (85 μg for 30 days) by mini-osmotic pump subcutaneously implanted betw...

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Bibliographic Details
Main Authors: Rong Zhang, Huifang Niu, Xiaohui Kang, Tao Ban, Hong Hong, Jing Ai
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2015-08-01
Series:Cellular Physiology and Biochemistry
Subjects:
Neuropeptide Y
Cardiac hypertrophy
Calcineurin
p38 MAPK
Online Access:http://www.karger.com/Article/FullText/430336

Internet

http://www.karger.com/Article/FullText/430336

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