Increasing ATP turnover boosts productivity of 2,3-butanediol synthesis in Escherichia coli

Increasing ATP turnover boosts productivity of 2,3-butanediol synthesis in Escherichia coli

Abstract Background The alcohol 2,3-butanediol (2,3-BDO) is an important chemical and an Escherichia coli producer strain was recently engineered for bio-based production of 2,3-BDO. However, further improvements are required for realistic applications. Results Here we report that enforced ATP wasti...

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Bibliographic Details
Main Authors: Simon Boecker, Björn-Johannes Harder, Regina Kutscha, Stefan Pflügl, Steffen Klamt
Format: Article
Language:English
Published: BMC 2021-03-01
Series:Microbial Cell Factories
Subjects:
Escherichia coli
Enforced ATP wasting
Biofuels
Two‐stage process
Butanediol
Productivity
Online Access:https://doi.org/10.1186/s12934-021-01554-x

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